Depression and loneliness can be prevented using structured telephone-based psychological care, delivered over 8 weeks, according to new research.
The results of the study, a major clinical trial carried out during the Covid-19 pandemic, showed rapid and enduring improvements in mental health and quality of life when older people received weekly phone calls over eight weeks from a specially trained coach who encouraged them to maintain their social connections and to remain active.
The study, led by a research team from our Trust and the University of York and Hull York Medical School, found levels of depression reduced significantly and the benefits were greater than those seen for antidepressants.
Participants in the study reported their levels of emotional loneliness fell by 21% over a three-month period and the benefits remained after the phone calls had ceased, suggesting an enduring impact.
Mitigating the psychological impacts of Covid-19
The Behavioural Activation in Social Isolation – BASIL+ trial started within months of the 2020 pandemic and was the largest trial ever undertaken to target and measure loneliness in this way. The study, published in the journal The Lancet [Healthy Longevity], represents a rapid advance in evidence to understand what works in preventing loneliness.
People invited to take part in the BASIL+ study were aged over 65 with multiple long-term conditions. They had been asked to shield during Covid-19 and were at a high risk of loneliness and depression.
The research was jointly led by Professor Simon Gilbody from the University of York and Hull York Medical School and Professor David Ekers from Tees, Esk and Wear Valleys NHS Foundation Trust.
Professor Ekers said, “Based on our previous research, we had a good idea what might work.
“With the support of the NHS and the NIHR we were able to test this in a large rigorous trial. The results are now available and this is very exciting. The UK led the world with the vaccine discovery trials.
“Similarly in mental health we have advanced the science of ‘what works’ in the area of loneliness, and we have learned much from the dark days of the pandemic.”
Professor Gilbody said: “We now know that loneliness is as bad for your health as smoking 15 cigarettes a day and depression is a silent killer. All of us working on the BASIL+ trial had older parents and relatives who became socially isolated during lockdown.”
Professor Ekers, Honorary Professor at the Mental Health and Addictions Research Group at the University of York and Professor Dean McMillan, Professor of Clinical Psychology at Hull York Medical School and University of York designed and led the telephone support programme.
Professor McMillan said: “An ounce of prevention is worth a pound of cure, and this trial shows how we can prevent both depression and loneliness.”
Professor Lucy Chappell, CEO of the National Institute for Health and Care Research, which funded the study, said: “These results are an important step forward in understanding what works in tackling and preventing loneliness and depression. The research is also a great example of how public money allows researchers, healthcare professionals and the public to work together across institutions and organisations to deliver results that will really make a difference to people’s health and wellbeing.”
Dr Liz Littlewood, the BASIL+ trial manager from the Department of Health Sciences, University of York, added: “This is what the UK does well and it shows how the NHS, Universities and third sector organisations were able to work in partnership during the pandemic to tackle the big health challenges.”
The BASIL+ trial was supported by a £2.6M award from the National Institute for Health and Care Research (NIHR) and was the only mental health trial prioritised by the NHS as part of its Urgent Public Health programme – a cornerstone of its fight against COVID. Hundreds of older people were recruited to the BASIL+ trial from 26 sites across the UK during the COVID pandemic of 2020-21.
The BASIL+ partnership included leading researchers from the Universities of Leeds, Keele, and Manchester and also the charity AgeUK.
